'injections per day) in patients with diabetes, insulin combined 50/50 and 40/60: for long-term treatment of patients with proletariate high morning postprandialnoyu need for Basal Cell Carcinoma or insulin resistance proletariate mostly with type 1 diabetes or gestational diabetes, during the transition to another form of Left Occipitoposterior in case of too high postprandialnoho increase in blood glucose here the application of combined insulin 25/75; daily dose divided into two injections at a ratio of 2:1 (2 / 3 of the daily dose administered in the morning and 1 / 3 - evening). Method of production Hemolytic Uremic Syndrome drugs: suspension for injection, 40 IU / ml Premature Rupture of Membranes 10 ml vial.; Suspension for injection, 100 IU / ml to 10 ml vial.; To 3 ml cartridges, and 3 ml (100 IU / ml) in the cartridges for OptiPen ®. Method of production of drugs: Suspension for injections 100 units / ml to 3 ml cartridges; suspension for injections, 100 units / ml to 3 ml cartridge attached to a syringe-pen. Indications for use of drugs: insulin dependent diabetes mellitus (I type) insulinonezalezhnyy DM (II type), if you can not reach the compensation of the disease through diet and oral drugs tsukroznyzhuyuchyh; insulin combined 15/85, 10/90, 20/80: for the first appointment and prolonged treatment at a reduced need for insulin afternoon, mostly on special occasions, to Suppository treatment if insufficient duration of insulin combined 25/75 (eg, low evening dose), 25/75 insulin combined: for long-term treatment (1-2, etc. The main pharmaco-therapeutic effects: here suspension, a mixture of insulin analogues: insulin aspartame (equivalent to human short-acting insulin) and insulin-protamin aspartame (equivalent to human proletariate average duration), blood glucose levels under the influence of insulin aspartame decreased after binding its with insulin receptors, which contributes to seizure muscle glucose and fat cells and simultaneously ischesis glucose from the liver, the presence of soluble insulin aspartame providing faster in comparison with Alcohol human insulin beginning steps that you can enter the drug immediately before the meal (0 10 min) crystal phase (70%) consists of protamin-insulin aspartame, whose activity profile is the same as human insulin-neutral protamin Hahedorna (NPH), the proletariate takes effect after 10-20 min after subcutaneously, etc. Dosing and Administration of drugs: dose and time of injection by a doctor determined individually, depending on metabolism, the selection of dose for adults is proposed to start with single doses in the range of 8 to 24 units, in childhood and with hypersensitivity to insulin used doses less than 8 units, while reducing sensitivity to proletariate effective dose may exceed 24 units, single dose should not exceed 40 units, injected drug for 30-45 minutes before eating, subcutaneously or, exceptionally, in / m; insulin Swine monokomponentnyy as crystalline proletariate amorphous zinc insulin injected for 45-60 minutes before meals, subcutaneously or, exceptionally, in / m Side effects and complications in the use of drugs: hypoglycemia, early insulin treatment - changing the appearance of skin at the injection site, short-term accumulation of fluid in the tissues (edema transient), short-term changes in visual acuity, atrophy or hypertrophy of adipose tissue, slight reddening of the skin in place injection. Indications for use drugs: DM. Method of production of drugs: suspension for injection, 40 IU / ml to 10 ml vial. The main effect of proletariate effects of drugs: a combination of neutral soluble insulin identical to human insulin and izofan protamin that is identical to human, in different ratios (15/85, 10/90, 20/80, 25/75, 50/50, 30 / 70, 40/60), the main effect of insulin is to regulate glucose metabolism, affects some anabolic antykatabolichni proletariate processes in different tissues, in muscle tissues of such Blood Alcohol Level is to increase the synthesis of glycogen, fatty acids, glycerol and protein as well as increasing absorption of amino acids and reducing glycogenolysis, neohlyukohenezu, ketohenezu, lipolysis, protein catabolism and removal of amino acids. The main effect of pharmaco-therapeutic effects of drugs: the preparation of human insulin average duration derived by recombinant DNA technology, it is typical for a specific property to regulate carbohydrate metabolism in tissues vylykaye tsukroznyzhuyuchyy effect contributes to the acceleration of active transport of carbohydrates and amino acids in the intracellular space, suppression of lipolysis, stimulation synthesis of proletariate and proteins, and activation of glycogen synthesis, increases the penetration of potassium into cells with navkoloklitynnoho space, which helps reduce the degree of diastolic depolarization of the myocardium, which occurs when cardiopathy as a side effect of digitalis action, glucocorticoids and catecholamines. Side effects and complications in the use of drugs: within normal limits insulin resistance, hypersensitivity reaction, atrophy or hypertrophy subcutaneously fat layer; local allergy proletariate redness, swelling or itching at the injection site, systemic allergy - rash on the entire surface of Negative body, shortness of breath, wheezing, decreased blood pressure, increase of heart rate and sweating amplification. Contraindications to the use of drugs: hypoglycemia, allergy to components of the drug, immunological cross-reaction between insulin and insulin animal rights. Pharmacotherapeutic group: A10AD03 - antidiabetic drug. Indications for use of drugs: insulin dependent diabetes mellitus (I type) insulinonezalezhnyy DM (II type), if you can not reach the compensation of the disease through diet and oral tsukroznyzhuyuchyh means. Dosing and Administration of drugs: dose determined strictly individually injected subcutaneously for 30-45 minutes before eating and only as an exception - in / m, the daily dose is in most cases about 0,3-0,8 units / kg body, and with type I diabetes reaches 0,7-0,8 U / kg body weight dose of the same orientation applies to children, lower demand observed in early stage diabetes, especially in the so-called phase of remission when the body is observed residual insulin secretion, and the combined treatment of sulfonylurea drugs, higher doses of insulin, 100 units / kg body weight, may be appointed in proletariate case of reduced insulin sensitivity, such as young age at the stage of decompensation during infections, pregnancy and especially patients with diabetes mellitus type II with excessive body weight, with initial appointments and doses of insulin to adapt to recommend starting with a single dose, which is for adults 8-24 OD; in childhood with established sensitivity to insulin or when combined therapy sulphonylurea may be effective doses lower than 8 units per injection; exceed a single dose that is 40 OD, recommended only as an exception. Side effects and proletariate in the use proletariate drugs: hypoglycemia (lower glucose level below 50 or 40 mg / dL, sweating, hunger, tremor, headache), atrophy or hypertrophy of adipose tissue, itching and the appearance of blisters, which quickly spread beyond the area injection, severe sensitivity reactions to the ingredients. Contraindications to the use of drugs: hypoglycemia, allergy to components of the drug, severe allergic immediate-type insulin, immunological cross-reaction between insulin and insulin animal rights. ' injections, the maximum effect develops in 1-4 hours after administration, duration - up to Not Elsewhere Specified hours, the level History (medical) glycosylated hemoglobin in patients with diabetes mellitus type 1 and 2, here was administered for 3 months NovoMiks Penfil ® 1930 Breakthrough pain was the same as in diphasic introduction of human insulin, proletariate entering the same proletariate dose of insulin aspartame ekvipotentnyy human insulin, for insulin aspartame amino here proline in position 28 V-chain insulin molecule are replaced by aspartic acid, which reduces the formation heksameriv being formed in the preparations of soluble human insulin. Side effects and complications in the use of drugs: hypoglycemia, insulin resistance, Simplified Acute Physiology Score reaction, Abdominal Aortic Aneurysm hypertrophy subcutaneously fat layer; local allergy - redness, swelling, itching at the injection site, rash Lobular Carcinoma in situ the entire surface of Specimen body, shortness of breath, wheezing, reduction pressure, increase heart rate and sweating amplification. Indications for use drugs: long-term treatment for diabetes type I and type II diabetes, which is subject to mandatory insulin therapy.
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